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Breaking Science News:
Fixing C15:0 Deficiencies Helps Slow Aging

The team behind the vision

Kim Kamdar, PhD

Co-Founder, Board Chair

<i>Kim</i> Kamdar, PhD

is a Partner at Domain Associates, a leading biotech venture capital group. With a background in small molecule drug discovery, Kim has been involved in cutting-edge therapeutic start-ups and has been a major part of identifying companies with promising molecular and companion diagnostics to support personalized medicine. Kim is co-founder and Chair of Seraphina Therapeutics and Truvian Sciences. Kim serves on the boards of Epic Sciences, Evofem Biosciences, Obalon Therapeutics, Sera Prognostics and Singular Genomics. She also helped to create and was formerly Chair of the board for Aspen Neuroscience and board member of Adastra Pharmaceuticals and Syndax Pharmaceuticals. Kim was involved with Ariosa Diagnostics until the company was sold to Roche in January 2015, Corthera until the company was sold to Novartis in February 2010 and BiPar Sciences until that company was sold to Sanofi in April 2009. Prior to Domain, Kim was a Kauffman Fellow and a research director at Novartis, where she built and led a research team that focused on the biology, genetics and genomics of model organisms to uncover small molecules that modulated signaling pathway networks. She received her B.A. from Northwestern University and her Ph.D. in biochemistry and genetics from Emory University.

Did you know?

Kim is the author of ten papers as well as the inventor on seven patents.


<b>Venn-Watson S</b>, Schork N (2023) Pentadecanoic acid (C15:0), an essential fatty acid, shares clinically relevant cell-based activities with leading longevity-enhancing compounds. Nutrients (in review).

<b>Venn-Watson S</b>, Butterworth CN (2022) Broader and safer clinically-relevant activities of pentadecanoic acid compared to omega-3: evaluation of an emerging essential fatty acid across twelve primary human cell-based disease systems. PLOS ONE 17:e0268778.

<b>Venn-Watson S</b>, Reiner J, Jensen ED (2022). Pentadecanoylcarnitine is a newly discovered endocannabinoid with pleiotropic activities relevant to supporting physical and mental health. Sci Rep 12:13717.

Venn-Watson S, Lumpkin R, Dennis EA (2020) Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential? Sci Rep 10:8161.

Venn-Watson S, Baird M, Novick B, Parry C, Jensen ED (2020) Modified fish diet shifted serum metabolome and alleviated chronic anemia in bottlenose dolphins (Tursiops truncatus): Potential role of odd-chain saturated fatty acids. PLOS ONE 15:e0230769.

Barratclough A, Gomez FM, Morey JS, Deming A, Parry C, Meegan JM, Carlin KP, Schwacke L, Venn-Watson S, Jensen ED, Smith CR (2020) Pregnancy profiles in the common bottlenose dolphin (Tursiops truncatus): Clinical biochemical and hematological variations during healthy gestation and a successful outcome. Theriogenol 142:92-103.

Le-Bert CR, Smith CR, Poindexter J, Ardente A, Meegan J, Wells RS, Venn-Watson S, Jensen ED, Sakhaee K (2018) Comparison of potential dietary and urinary risk factors for ammonium urate nephrolithiasis in two bottlenose dolphin (Tursiops truncatus) popualtions. Am J Physiol Renal Physiol 315:F231-F237.

Eberle KC, Venn-Watson S, Jensen ED, LaBresh J, Sullivan Y, Kakach L, Sacco RE (2018) Development of testing of species-specific ELISA assays to measure IFN-γ and TNF-α in bottlenose dolphins (Tursiops truncatus). PLOS ONE 13:e0190786.

Standorf K, Cortex-Hinjosa G, Venn-Watson S, Rivera R, Archer L, Wellehan Jr JFX (2018) Phylogenetic analysis of the genome of an enteritis-associated bottlenose dolphin mastadenovirus supports a clade infecting the cetartiodactyla. J Wildlf Dis 54: 112-121.

Borras E, Aksenov AA, Baird M, Novick B, Schivo M, Zamuruyev KO, Pasamontes A, Parry C, Foutouhi S, Venn-Watson S, Weimer BC, Davis CE (2017) Exhaled breath condensate methods adapted from human studies using longitudinal metabolomics for predicting early health alterations in dolphins. Analyt Bioanalyt Chem 409:6523-6536.

Hofstetter AR, Eberle KC, Venn-Watson S, Jensen ED, Porter TJ, Waters TE, Sacco RE (2017) Monitoring bottlenose dolphin leukocyte cytokine mRNA responsiveness by qPCR. PLOS ONE 12:e0189437.

Elnaggar MM, Abdellrazeq GS, Venn-Watson S, Jensen ED, Hulubei V, Fry LM, Sacco RE, Davis WC (2017) Identification of monoclonal antibodies cross-reactive with bottlenose dolphin orthologues of the major histocompatibility complex and leukocyte differentiation molecules. Vet Immunol and Immunopath 192:54-59.

Meet the rest of our team